Symbol
Name
ID

Tmco1
transmembrane and coiled-coil domains 1
MGI:1921173

Phenotype annotations related to reproductive system

Darker colors indicate more annotations

Human Phenotypes	Shawl scrotum
Disease(s) Associated with TMCO1	Shawl scrotum
craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development syndrome 1

Mouse Phenotypes

oocyte degeneration

increased granulosa cell apoptosis

abnormal ovary morphology

absent corpus luteum

abnormal ovarian follicle morphology

decreased primary ovarian follicle number

decreased primordial ovarian follicle number

decreased secondary ovarian follicle number

absent ovarian follicles

increased atretic ovarian follicle number

impaired ovarian folliculogenesis

decreased ovary weight

small ovary

premature ovarian failure

decreased superovulation rate

female infertility

reduced female fertility

decreased litter size

Availability

Mouse Genotype

Tmco1^em1(IMPC)J/Tmco1^em1(IMPC)J

Tmco1^em1Smoc/Tmco1^em1Smoc

Tmco1^tm1Tsta/Tmco1^tm1Tsta

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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